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10 articles found
Priya Nair
Cryptosporidiosis is a major cause of pediatric diarrheal illness in low-resource settings. This study applies molecular typing to characterize Cryptosporidium species and subtype diversity among children under five presenting with acute diarrhea.
Carlos Herrera, Lucia Fernandez
Chagas disease continues to affect rural populations across Latin America. This multi-country serological survey estimates seroprevalence and identifies key risk factors for Trypanosoma cruzi exposure in six endemic regions.
Ahmed Farouk
Gastrointestinal nematode infections cause substantial productivity losses in small ruminant husbandry. This study assesses parasite burden and benzimidazole anthelmintic efficacy across sheep and goat flocks in the Nile Delta region.
James O'Connell
Whole-genome sequencing was used to track methicillin-resistant Staphylococcus aureus (MRSA) transmission dynamics within intensive care units over a two-year period, revealing distinct clonal lineages and cross-ward transmission events.
Elena Petrov, Michael Brandt
Timely diagnosis of visceral leishmaniasis remains a challenge in resource-limited settings. We evaluate the field performance of a novel rK39-based rapid diagnostic test against parasitological gold-standard methods in an endemic East African cohort.
Kwame Asante
Hepatic granuloma formation in response to Schistosoma mansoni eggs drives progressive fibrosis in chronic schistosomiasis. We characterize the cellular composition and cytokine milieu of granulomas at sequential stages of infection in a murine model.
David Whitfield, Sarah Blackwood
Geographic variation in Aedes aegypti vector competence significantly influences dengue transmission dynamics. This study compares infection, dissemination, and transmission rates across mosquito populations from four dengue-endemic countries.
Mei Lin Tan
Toxoplasma gondii establishes chronic infection within the central nervous system by modulating neuronal and glial cell responses. We investigate the molecular mechanisms of parasite persistence and the resulting neuroinflammatory profile in an in vitro neural cell model.
Fatima Al-Hassan, Noura Al-Mutairi
Uropathogenic E. coli (UPEC) is the leading cause of urinary tract infections worldwide. This surveillance study evaluates antimicrobial susceptibility profiles of UPEC isolates from three tertiary hospitals, highlighting rising resistance to fluoroquinolones and extended-spectrum beta-lactams.
Amina El-Sayed, Youssef Nabil
Artemisinin resistance in Plasmodium falciparum is closely linked to mutations in the Kelch13 propeller domain. This study characterizes the prevalence and functional impact of Kelch13 polymorphisms across clinical isolates from endemic regions, providing insight into resistance surveillance strategies.
